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H1N1 viruses gain Tamiflu resistance without losing fitness

first_imgMar 2, 2009 (CIDRAP News) – Studies published today confirm that influenza A/H1N1 viruses have become widely resistant to oseltamivir (Tamiflu), the leading flu drug, without losing their ability to make people sick—thereby underlining the need for new antiviral drugs.The findings also underscore the possibility that H5N1 avian influenza could gain resistance to oseltamivir, calling into question the value of stockpiling the drug in preparation for a potential flu pandemic, according to two experts who comment on the latest findings in an accompanying editorial. The research reports and editorial were released online today by the Journal of the American Medical Association.To the surprise of many, H1N1 resistance to oseltamivir rose sharply last year, reaching 12.3% in the United States and 16% worldwide. So far this season, it is far higher: more than 98% (321 of 325) of H1N1 isolates tested by the Centers for Disease Control and Prevention (CDC) were resistant to the drug.None of the H1N1 isolates have shown resistance to zanamivir (Relenza), the other flu drug in the neuraminidase inhibitor class. H1N1 is one of three flu subtypes that circulate each season, along with A/H3N2 and influenza B.Because of the spread of resistance, the CDC in December changed its recommendations on antiviral treatment for flu. For patients suspected of having influenza A, the CDC recommended using zanamivir or a combination of oseltamivir and rimantadine (an older flu drug in a different class) instead of oseltamivir alone.In one of the new studies, a team from the CDC and several state health departments compared people infected with oseltamivir-resistant and oseltamivir-susceptible strains of H1N1 last season and found no differences in patient characteristics, symptoms, or severity of illness. They report that four patients infected with resistant strains died.A second study describes an outbreak of resistant H1N1 infections in four patients in a Dutch hospital in February 2008. Three immunocompromised patients became ill after exposure to a patient who was sick with a resistant H1N1 strain, and genetic analysis showed that the viruses all matched, making it clear that the infection spread from person to person in the hospital.Taken together, the two studies “dispel the notion that oseltamivir resistance compromises virulence,” states the accompanying editorial by David M. Weinstock, MD, and Gianna Zuccotti, MD, of Harvard Medical School in Boston.Resistance in 2007-08 US seasonThe CDC-state study reports that oseltamivir resistance was found in 142 of 1,155 (12.3%) H1N1 viruses tested last season. Resistant viruses were reported in 24 states. Of the 142 patients who had resistant viruses, 99 supplied information.None of the 99 reported taking oseltamivir before being tested for flu, nor did they have close contact with others who had taken it. Four of the patients died, two of them in hospitals and the other two on the way to a hospital or in the emergency department.After seven cases from one state were excluded, the authors compared 92 patients who had resistant H1N1 infections with 182 who had susceptible strains. They found no differences by age, sex, race, underlying medical conditions, or clinical symptoms.The analysis did indicate that patients with susceptible viruses were more likely to be hospitalized, but this difference disappeared when the two patients with resistant viruses who died before they could be admitted to hospitals were classified as hospital admissions.Before last season, oseltamivir resistance had been seen only in patients who were treated with the drug, the authors note, adding that it is unclear why oseltamivir-resistant H1N1 viruses emerged during the season and continue to circulate.”Additional options for the treatment and prophylaxis are critically needed,” the report concludes.Hospital outbreakIn the other report, the Dutch researchers write that three hospital patients apparently acquired oseltamivir-resistant H1N1 infections from another patient who was found to have the virus while being treated for systemic lupus erythematosus.The three were in the same ward as the presumed index patient at the same time, though they never shared a room. Two patients, a hematopoietic stem-cell transplant recipient and an 89-year-old man, died of the illness.Genetic sequencing revealed that isolates from the four patients matched closely. All four had not only the H274Y mutation associated with resistance, but also a rare mutation known as T284A.Five healthcare workers got sick with flu-like symptoms while the index patient was hospitalized, but none of them were tested for flu, the report says.”This study confirmed that circulating H274Y-mutated A(H1N1) viruses can retain significant pathogenicity and lethality, as shown in these elderly or immunocompromised patients with lymphocytopenia, underlining the need for the introduction of new effective antiviral agents and therapeutic strategies,” the authors conclude.Findings shouldn’t be surprising”The widespread belief that oseltamivir would retain activity against epidemic influenza strains has crumbled, but this should come as no surprise,” write Weinstock and Zuccotti, in the editorial accompanying the two reports. They say that surveillance over the past several years indicated that resistance was rising on a path that closely paralleled the rise of adamantane (amantadine and rimantadine) resistance 3 years earlier.Further, recent laboratory studies have shown that the H274Y mutation that confers resistance in H1N1 viruses does not necessarily interfere with the virus’s ability to replicate in animal models, the editorial says.One corollary of the new studies, according Weinstock and Zuccotti, is that “oseltamivir resistance is likely to develop during the treatment of other N1-containing strains, including avian influenza A(H5N1). Thus, stockpiles to mitigate an influenza pandemic should not be limited oseltamivir.”Oseltamivir is the leading antiviral drug in national stockpiles for pandemic preparedness. The US stockpile is about 80% oseltamivir and 20% zanamivir, federal officials have said.Vaccination remains key toolOther experts said the findings show that vaccination remains the key tool for battling influenza. They share the concern about the risk of resistance in H5N1 viruses.”These developments further support the use of influenza vaccine as the cornerstone for influenza prevention and control,” said Kathleen M. Neuzil, MD, MPH, a member of the Pandemic Influenza Task Force of the Infectious Diseases Society of America and director of the Influenza Vaccine Project at PATH in Seattle.Concerning the risk of resistance in H5N1, she said, “These recent findings represent a paradigm shift. We need to be prepared for the possibility that H5N1, or other influenza strains, could become resistant to oseltamivir and still be pathogenic and transmissible. This advocates for research and development into new antiviral and effective pandemic vaccines.”Dr. Keiji Fukuda, director of the World Health Organization’s Global Influenza Programme, called H5N1 resistance “a theoretical possibility.””So far, oseltamivir resistance has been rarely reported in H5N1 human isolates (three in Vietnam with H275Y mutation, two in Egypt with N294S mutation which confers mild reduction of oseltamivir susceptibility),” he commented by e-mail. “This is another situation where monitoring is essential.” (The resistance mutation is sometimes called H275Y, depending on the naming system.)Fukuda observed that all the resistant H1N1 viruses tested so far have been sensitive to zanamivir and the adamantanes. “Of course, empiric therapy is difficult when you do not know the specific influenza virus type and subtype—as one typically does not in clinical practice—because in some countries most of the circulating H3N2 viruses are resistant to adamantanes,” he added. “But when national surveillance is good, empirically selected therapy is rational and possible.”Both experts allowed for a possibility that H1N1 will eventually become susceptible to oseltamivir.”As these [resistant Brisbane-like] strains continue to evolve and be replaced by other strains, it’s possible that the resistance will go down. This needs to be monitored,” said Fukuda.Neuzil commented, “No one knows, but it [resistance] could certainly disappear as rapidly as it developed, as without widespread use of oseltamivir, it appears unlikely that antiviral pressure will favor resistant viruses.”Dharan NJ, Gubarcva LV, Meyer JJ, et al. Infections with oseltamivir-resistant influenza A(H1N1) virus in the United States. JAMA 2009;301(10) (early online publication) [Full text]Gooskens J, Jonges M, Claas ECJ, et al. Morbidity and mortality associated with nosocomial transmission of oseltamivir-resistant influenza A(H1N1) virus. JAMA 2009;301(10) (early online publication) [Full text]Weinstock DM, Zuccotti G. The evolution of influenza resistance and treatment. (Editorial) JAMA 2009;301(10) (early online publication) [Full text]See also: CDC’s weekly flu surveillance report 19, 2008, CIDRAP News story “With H1N1 resistance, CDC changes advice on flu drugs”last_img read more

Picking up the gauntlet thrown down by Property Week

first_imgWould you like to read more?Register for free to finish this article.Sign up now for the following benefits:Four FREE articles of your choice per monthBreaking news, comment and analysis from industry experts as it happensChoose from our portfolio of email newsletters To access this article REGISTER NOWWould you like print copies, app and digital replica access too? SUBSCRIBE for as little as £5 per week.last_img

New bid but little hope to reform UN Security Council

first_imgA coalition of four nations — Brazil, Germany, India and Japan — on Wednesday renewed its campaign for inclusion.Adding the “G4″ would ensure that the Security Council incorporate Europe’s biggest economy (Germany), the world’s second largest developed economy and major UN contributor (Japan), the world’s second most populous nation (India) and the most populous nation in Latin America (Brazil).”The world of today is very different from what it was when the United Nations was created 75 years ago,” their four foreign ministers said in a joint statement after talks by videoconference on the sidelines of the UN General Assembly, held virtually this year due to the Covid-19 pandemic.”Only if we manage to reform the Security Council will we stop it from becoming obsolete,” they said. A flurry of world leaders have appealed again to the United Nations to reform the Security Council, reviving a bid launched 15 years ago.But chances of transforming the world’s body most powerful institution are seen as close to zero by most experts, who see little incentive from today’s Permanent Five to let others in.Britain, China, France, Russia and the United States hold veto-wielding permanent seats at the Security Council, an arrangement that reflects the geopolitical dynamics at the time of the UN’s creation in the aftermath of World War II. ‘Best reflection’ Leaders from around the world called at the UN General Assembly for a more representative Security Council.South African President Cyril Ramaphosa said that Africa needed to be better represented in order “to collectively resolve some of the world’s most protracted conflicts.”In 2005, African nations adopted a common platform to seek two permanent seats on the Security Council but discussions have failed to determine which countries those would be.Angolan President Joao Lourenco called for a Security Council “that is the best reflection of peoples, nations and continents,” while President Felix Tshisekedi of the Democratic Republic of Congo called for a body that is “more transparent, more democratic and more representative.”President Carlos Alvarado of Costa Rica, a nation with no standing army, said that the top UN body should be rechristened the “Human Security Council,” deploring how the world’s major arms exporters were represented.The (Human) Security Council must be “capable of overcoming the major internal divisions to work together with one sole voice,” he said.Chilean President Sebastian Pinera similarly said that the Security Council “is no longer responding to the needs and challenges of our time.””We must be the architects of our new common home,” Argentine President Alberto Fernandez said. “We need a UN 4.0.” Topics : Who want to lose power? But to include more nations, the Permanent Five would dilute their own status.The chances of Security Council reform “are next to none,” said Andrew Bacevich, professor emeritus of international relations and history at Boston University.”And the reason is that the reform proposal, which in many respects makes great sense, calls upon the Permanent Five countries to lose their power, he said.”I can’t imagine why any of them would find that prospect agreeable.”The United States has backed a seat for close ally Japan, and former president Barack Obama on a visit to India announced support for New Delhi’s bid.But the United States is hardly pressing for an expansion, and showed hesitation in 2005 amid tensions with Germany over the Iraq invasion.With Britain’s exit from the European Union, France is the only EU nation with a Security Council veto. But France officially backs the bid by the four nations including Germany, as well as an expanded African presence, and unlike Russia, the United States and China seeks to limit the use of the veto to questions involving mass atrocities.last_img read more

Gov. Wolf Calls for Legislative Action to Help Homeowners and Renters Avoid an Eviction Cliff

first_img Economy,  Press Release With rent and mortgage debt mounting for hundreds of thousands of Pennsylvanians, Governor Tom Wolf is calling on the General Assembly to fix a state relief program to prevent many families from becoming homeless and enact a moratorium on evictions and foreclosures until the end of the year. The governor was joined today by legislators and housing advocates at a press conference in Lancaster County.“Pennsylvania is still racing toward an eviction cliff when thousands of families will face months of unpaid rent and fees,” said Gov. Wolf. “We must address the mounting rent debt to help tenants stay in their home and allow landlords to pay their mortgages.“If the legislature does not act to fix the state’s relief program, even more families may be facing homelessness on Jan. 1, during the coldest time of the year. That would be terrible for families and will strain local social services and taxpayers that are already stretched to the limit by the pandemic.”Legislation is needed to ensure people have a stable place to live after the governor’s executive order pausing evictions and foreclosures expired on Aug. 31. The governor signed the orders on May 7 and July 9 as a Pennsylvania Supreme Court eviction moratorium expired in May. The state’s Emergency Services Code does not allow the governor to provide further relief related to temporary housing.The Centers for Disease Control and Prevention halted some rental evictions nationwide until Dec. 31, however some tenants and all homeowners are still at risk. It is a temporary Band-Aid that does not stop foreclosures or help landlords who are struggling to pay mortgages and local property taxes. Nearly 400,000 Pennsylvanians, approximately 17 percent of renters in the state, are at risk of being evicted, according to the Housing Alliance of Pennsylvania.In addition to legislation to pause evictions, the governor is again urging the legislature to improve the CARES Rent Relief Program and provide an extra $100 million in CARES funding. Enacted in May, the program provides $150 million in rent relief and $25 million in mortgage relief, but is helping fewer people than intended. According to the Pennsylvania Housing Finance Agency, which administers the program and is recommending changes, 16,600 tenants applied for $31.7 million in relief in August, however only 1,756 tenants were approved for $3.3 million because of the cumbersome application process.The governor called for legislation with the following program changes to help more renters and homeowners:Raise the $750 monthly cap on rent relief to at least 130% of HUD limits – In some parts of the state rent payments exceed $750 a month, therefore landlords decline to participate, leaving tenants without payment assistance.Eliminate the requirement that households be 30 days behind on rent to be eligible for assistance – The requirement creates an unfair burden on applicants who prioritize rent and mortgage payments over paying for food, medicine or other bills.Eliminate verification that applicants applied for unemployment compensation – The added administrative step creates unnecessary processing delays of applications and availability of assistance.Provide landlords and mortgagees the option to forgive the remaining unpaid rent or mortgage payments or allow the balance to be repaid over one year – Offering property owners to recoup balance of payments should encourage participation in the program.“Our data from July and August shows clearly that demand for rent and mortgage relief is there,” said Bryce Maretzki, PHFA’s director of planning and policy. “If we can work with the legislature to remove some of the barriers that are keeping people from applying, or from qualifying for assistance, then our federal CARES funding can really fulfill its intended purpose by keeping people in their homes during the economic downturn.”“Every person deserves a decent, affordable, and safe place to live,” said Sen. Tim Kearney. “In a pandemic, ensuring housing stability is not just a moral imperative but also a public health necessity. The General Assembly must act now to help keep people in their homes. Families across Pennsylvania are facing an emergency at their doorsteps, and they are waiting for us in the General Assembly to do our job.”Rep. Malcolm Kenyatta added, “Pennsylvanians are struggling and we in the Legislature have a duty to act — and do so quickly. This isn’t political, it’s personal. I know what it means to be housing insecure and many families are now gripped with that same fear. I stand with Gov. Wolf in urging the Republican majority to bring our legislative package to the floor for a vote.”As part of his fall legislative agenda for worker and family support and protections, COVID-19 recovery, and government reform, the governor is proposing $100 million in grants to help Pennsylvanians with utility costs. The funds would be divided between the Low-Income Home Energy Assistance Program (LIHEAP) and a new emergency water/wastewater program administered by PENNVEST.The Pennsylvania Utility Commission (PUC) recently reported that at least 800,000 utility customers across the state are currently in active termination status and would be at risk of having their electricity, water or gas shut off had the PUC not implemented a termination moratorium at the start of COVID.Ver esta página en español. Gov. Wolf Calls for Legislative Action to Help Homeowners and Renters Avoid an Eviction Cliff SHARE Email Facebook Twittercenter_img September 08, 2020last_img read more

The growth suburbs to watch

first_img14 Lovedale St will go under the hammer next weekenedMr Macmillan said Wilston was “the best suburb in Australia”.“There was a referendum on it, didn’t you hear?” he joked. He said they had seen a rise in buyer demand in recent times, with the number of open home attendees and buyer confidence up.Mr Macmillan said Wilston’s proximity to the city, good schools, the views and the local cafes and amenities were big sellers. Brisbane home values on the rise The latest CoreLogic Market Trends report shows that Burbank is now Brisbane’s third most expensive suburb, only behind Teneriffe ($1.86 million) and New Farm ($1,622,500).Burbank is listed as a high demand suburb by and is dominated by older couples and families. It boasts large family homes, acreage estates and lifestyle properties.Also hitting well above the Brisbane median house price growth average is Chelmer (up 14.3 per cent), Upper Brookfield (9.2%), New Farm and Wilston (both up 8.2%).The top suburbs for units were Alderley (up 18.3%), Manly (17.8%), Grange (14.6%), Bulimba (9.2%) and Carindale (6.9%). 14 Lovedale St even has one of the most sought-after features — a pool“With the median house price now above $1 million, most of the buyers we are talking to live in or near the area and are keen to upgrade,” he said. “Most of these are second or third house buyers with young families and kids in primary school.” Pimped out Queenslander sold in 24 hours Video Player is loading.Play VideoPlayNext playlist itemMuteCurrent Time 0:00/Duration 1:58Loaded: 0%Stream Type LIVESeek to live, currently playing liveLIVERemaining Time -1:58 Playback Rate1xChaptersChaptersDescriptionsdescriptions off, selectedCaptionscaptions settings, opens captions settings dialogcaptions off, selectedQuality Levels720p720pHD576p576p360p360p216p216pAutoA, selectedAudio Tracken (Main), selectedFullscreenThis is a modal window.Beginning of dialog window. Escape will cancel and close the window.TextColorWhiteBlackRedGreenBlueYellowMagentaCyanTransparencyOpaqueSemi-TransparentBackgroundColorBlackWhiteRedGreenBlueYellowMagentaCyanTransparencyOpaqueSemi-TransparentTransparentWindowColorBlackWhiteRedGreenBlueYellowMagentaCyanTransparencyTransparentSemi-TransparentOpaqueFont Size50%75%100%125%150%175%200%300%400%Text Edge StyleNoneRaisedDepressedUniformDropshadowFont FamilyProportional Sans-SerifMonospace Sans-SerifProportional SerifMonospace SerifCasualScriptSmall CapsReset restore all settings to the default valuesDoneClose Modal DialogEnd of dialog window.This is a modal window. This modal can be closed by pressing the Escape key or activating the close button.Close Modal DialogThis is a modal window. This modal can be closed by pressing the Escape key or activating the close button.PlayMuteCurrent Time 0:00/Duration 0:00Loaded: 0%Stream Type LIVESeek to live, currently playing liveLIVERemaining Time -0:00 Playback Rate1xFullscreenWhy location is everything in real estate01:59The Greater Brisbane median house price grew by 0.6 per cent over the three months to April.But there are suburbs that are blitzing that average, with the greenbelt suburb of Burbank recording a whopping 22.5 per cent increase in median house prices over that same period.Eleven houses sold in the emerging suburb over that three-month stretch, with the median price jumping to $1,518,888. MORE NEWS: Inside the most expensive house for sale in the US Pics of Brisbane skyline and Skytower (tallest building). Pic Annette DewOverall, taking into account growth in both house and unit values, the biggest growth suburbs were Burbank (houses), Alderley (units), Manly (units), Grange (units) and Chelmer (houses).More than 50 Brisbane City Council suburbs recorded growth equal to or above that in the Greater Brisbane region, that is above 0.6 per cent.Of those suburbs in the Top 10 for growth, eight had a median house price above $1 million.Only Corinda, which rose 7.3 per cent to $805,000, and Yeerongpilly, up 6.1 per cent to $812,500, were below the $1 million mark.More from newsNoosa unit prices hit new record high as region booms: REIQ12 hours agoParks and wildlife the new lust-haves post coronavirus12 hours agoWilston, another high demand suburb, averaged 1354 visits per property listing compared with 373 for the average Queensland listing. Going to auction next Saturday is 14 Lovedale St at Wilston, which is listed with Alistair Macmillan of Ray White Wilston. Where the struggle is real for renters Three month growth – median house prices Source: CoreLogiclast_img read more

Poyet eyes swoop for Seagulls duo

first_imgSunderland boss Gus Poyet is ready to return to former club Brighton to make a double swoop for Liam Bridcutt and Will Buckley. Press Association Sport understands the Black Cats are in advanced talks with the Seagulls over the midfield duo, both 24, as Poyet attempts to strengthen his squad for a concerted fight against relegation from the Barclays Premier League. The Uruguayan’s interest in the pair has been no secret, but the news that deals could be close is encouraging for the manager, whose first signing will be officially completed on New Year’s Day when Fiorentina full-back Marcos Alonso joins on loan for the rest of the season. Press Associationcenter_img Poyet revealed on Monday that he hoped to add up to four players to his squad during the winter transfer window with owner and chairman Ellis Short prepared to back him, although not with unlimited funds. Director of football Roberto De Fanti, of course, presided over a summer spending spree which saw the club recruit no fewer than 14 players, a policy which has yielded limited results. The fact that Sunderland are now engaged in the process of trying to land the Brighton pair suggests the manager is having a greater say on transfers than predecessor Paolo Di Canio, something he indicated he wanted shortly after his arrival on Wearside as the ill-fated Italian’s replacement. Holding midfielder Bridcutt has made 11 appearances to date for the Seagulls this season while winger Buckley has 19 to his name. Poyet would not be drawn on possible outgoings from the club during January, but nine members of the squad are out of contract at the end of the current season and that could be significant. last_img read more

Officials: Some Evidence Does Not Support Criminal Charge in George Floyd’s Death

first_imgHe added that his office has received calls and emails asking, “What are you gonna do about the murder of George Floyd?”“We are going to investigate it as expeditiously, as thoroughly and completely as justice demands,” Freeman said. “Sometimes that takes a little time, and we ask people to be patient. We have to do this right.”“That video is graphic and horrific and terrible, and no person should do that,” he continued. “But my job in the end is to prove that he violated criminal statute. And there is other evidence that does not support a criminal charge. We need to wade through all of that evidence to come through with a meaningful determination, and we are doing that to the best of our ability.”Freeman, MacDonald and other officials asked protesters to keep their demonstrations peaceful and to avoid harming innocent individuals and businesses.“We support peaceful demonstration,” Freeman said. “Violence hampers our case, it takes valuable police resources away from our investigation, and it also harms innocent people.” Investigators added that county, state and federal offices are working together on separate investigations into Floyd’s death.Hennepin County Attorney Mike Freeman, who also spoke at the news conference, said his office had already prosecuted and convicted a police officer for “unreasonable use of deadly force.”Please stay home. Please do not come here to protest. Please keep the focus on George Floyd, on advancing our movement, and on preventing this from ever happening again. We can all be in that fight together.— Melvin Carter (@melvincarter3) May 28, 2020 Federal and local investigators urged residents in Minneapolis, Minn. to remain calm on Thursday, as violent protests continued following the death of George Floyd.However, they stopped short of announcing any charges against the police officers involved in the case, saying they needed more time to do their jobs.Floyd, a 46-year-old black man, died in police custody this week after a white officer was shown on video pinning him to the ground with a knee on the man’s neck for several minutes.center_img Derek Chauvin, a 19-year veteran of the police force, has a service record that includes three shootings and nearly 20 complaints.Floyd, who was heard on the video saying he could not breathe, died later the night of the shooting.“It’s imperative that the community understands how seriously we are taking this,” U.S. Attorney Erica MacDonald said during a news conference Thursday evening.last_img read more

Commission Rejects President Trump’s Request for Early Debate

first_imgThe Commission on Presidential Debates said Thursday that it sees no need to change the schedule of this year’s debates, after President Trump’s campaign called for a debate to be held in early September.The campaign cited an expected surge in early voting due to the pandemic as the reason for the request.“While more people will likely vote by mail in 2020, the debate schedule has been and will be highly publicized,” commission co-chairs Frank Fahrenkopf, Dorothy Ridings, and Kenneth Wollack wrote in a letter to Trump campaign attorney Rudy Giuliani. “Any voter who wishes to watch one or more debates before voting will be well aware of that opportunity.”The Commission on Presidential Debates previously announced three presidential debates on Sept. 29, Oct. 15, and Oct. 22, as well as one vice presidential debate on Oct. 7.Giuliani noted to the commission that 16 states will have already started voting by Sept. 29, calling the existing schedule “an outdated dinosaur and not reflective of voting realities in 2020.”NEWS Commission on Presidential Debates rejects Giuliani’s request for a fourth debate in early Sept, saying voters who get their ballots before the first scheduled debate are not compelled to submit them before the debate. They also push back on his request to choose moderators.— Jennifer Epstein (@jeneps) August 6, 2020 However, the Biden campaign rejected previous efforts by Giuliani and the Trump campaign in June to schedule more debates and hold them sooner.Meanwhile, both campaigns have asked the commission to finalize contingency plans and logistics in case other obstacles develop.In addition, Democrats agree that a schedule change is a valid suggestion.“The presidential debates should be moved up in the schedule to reflect large numbers voting by mail and must include questions from real people – whether they are in the audience or not,” said Democratic strategist Bradley Honan.Biden announced Wednesday that he will not travel to Milwaukee to accept the Democratic nomination in person later this month.Despite consistently being among the most-watched television events of an election year, presidential debates rarely have a significant impact on the actual race. The COVID-19 outbreak has resulted in events being cancelled and conventions being scaled back.“Certainly former Vice President Biden would agree with the need to avoid having millions of Americans disenfranchised by not being able to see and hear the two major party candidates debate before they have ballots in-hand,” Giuliani wrote.However, the commission chairs responded that voters who receive ballots before Sept. 29 will be under no obligation to return them until after all of the debates are held.They added that an additional debate would be considered if both Trump and Biden agree to it.On Thursday, President Trump tweeted:How can voters be sending in Ballots starting, in some cases, one month before the First Presidential Debate. Move the First Debate up. A debate, to me, is a Public Service. Joe Biden and I owe it to the American People!— Donald J. Trump (@realDonaldTrump) August 6, 2020last_img read more

Wisconsin hit with more injuries

first_imgJEFF SCHORFHEIDE/Herald photoBret Bielema confirmed Monday what he hinted at followingWisconsin’s 38-17 loss to Ohio State Saturday: His team suffered two moreseason-ending injuries.The UW head football coach and his staff will need to devisegame plans for the remainder of the season without the services of two regularstarters: cornerback Allen Langford and defensive tackle Jason Chapman.Both players will undergo season-ending knee surgery as soonas swelling in the injured areas decrease enough to have the necessaryprocedures. Those injuries, along with a leg injury of unknown severityto offensive tackle Eric Vanden Heuvel, built on what has become an overridingtheme of attrition for this Wisconsin football team. Seemingly every game, keyor emerging playmakers have gone down with injuries.“I think we’ve lost five offensive starters for one, if notmultiple games, and defensively the same thing,” Bielema said at his weeklypress conference. “It’s not an excuse, but you realize how much of an effectthose things cumulatively have, just being able to practice and go about andhave accountability and dependability.”One of the offensive players missing from last week’s tiltwith Ohio State was running back P.J. Hill. Hill was sidelined for that contest with a bruised leg, andaccording to Bielema, may not be ready to go come Saturday’s game againstMichigan.“Really it’s on P.J.,” Bielema said. “Whenever P.J. feels hecan come back”last_img read more